Early-stage lung cancer detection via thin-section low-dose CT reconstruction combined with AI in non-high risk populations: a large-scale real-world retrospective cohort study
These findings highlight the importance of expanding lung cancer screening to non-high-risk populations, especially never-smokers. LDCT-TRAI outperformed traditional LDCT in detecting early-stage cancers and improving survival outcomes, underscoring its potential as a more effective screening tool for early lung cancer detection in this population.
Authors
- Jun Tang
- Miye Wang (ORCID: https://orcid.org/0000-0002-4137-0310)
- Jinnan Li (ORCID: https://orcid.org/0009-0001-2600-956X)
- Xuejun Zhuo (ORCID: https://orcid.org/0000-0002-0366-6997)
- Yu He (ORCID: https://orcid.org/0000-0003-0523-6082)
- Guiyi Ji
- Jinghong Xian
- Tingting Song (ORCID: https://orcid.org/0000-0002-6740-2085)
- Bojiang Chen (ORCID: https://orcid.org/0000-0002-4882-9817)
- Lili Jiang
- Feng Chen (ORCID: https://orcid.org/0000-0002-9129-7895)
- Rui Zhang (ORCID: https://orcid.org/0000-0002-2559-6686)
- Wenxin Luo (ORCID: https://orcid.org/0000-0002-0557-3196)
- Weimin Li
- Jun Shao
- Tao Zheng (ORCID: https://orcid.org/0000-0002-1820-1762)
- Chengdi Wang (ORCID: https://orcid.org/0000-0002-8691-6903)
- Ming Yang (ORCID: https://orcid.org/0000-0001-9612-8073)
- Weiwei Song (ORCID: https://orcid.org/0000-0003-2547-6155)
- Xiaolong Tang (ORCID: https://orcid.org/0000-0001-5105-850X)
- Yuan Zhu (ORCID: https://orcid.org/0009-0000-3948-1989)
- Min Feng (ORCID: https://orcid.org/0009-0006-7527-0437)
- Renxin Ding
- Pei-Ji Yao
Institutions
- Army Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Sichuan University (CN)
- West China Medical Center of Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Precision Clinical Medicine
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1093/pcmedi/pbaf007
- Citations
- 1
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52