Improved NTCP model for late radiation-induced aspiration based on dose delivered to specific aspiration-related OARs

NTCP models for late aspiration may be improved by including the dose to aspiration-related OARs, defined by the FSU concept. In addition to the supraglottic larynx, sparing of the Anterior Segment, HSG and UES could further decrease the risk of radiation-induced aspiration, but this remains to be confirmed in clinical studies.

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Publication Details

Journal
Radiotherapy and Oncology
Published
2025-03-29
DOI
https://doi.org/10.1016/j.radonc.2025.110871
Citations
4
Primary Topic
Dysphagia Assessment and Management
Type
article
Field-Weighted Citation Impact
12.47

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article

Improved NTCP model for late radiation-induced aspiration based on dose delivered to specific aspiration-related OARs

Johannes A. Langendijk, Hans Paul van der Laan, Martijn Veening, A. van der Schaaf et al.
4 citations
Radiotherapy and Oncology
Dysphagia Assessment and Management
12.47
article

Improved NTCP model for late radiation-induced aspiration based on dose delivered to specific aspiration-related OARs

Johannes A. Langendijk, Hans Paul van der Laan, Martijn Veening, A. van der Schaaf, Marije R. Vergeer, A. Gawryszuk, Johanna G.M. van den Hoek, Rico N. P. M. Rinkel, R.J.H.M. Steenbakkers, Irma M. Verdonck‐de Leeuw, Jan Wedman
article en
4 citations

Abstract

NTCP models for late aspiration may be improved by including the dose to aspiration-related OARs, defined by the FSU concept. In addition to the supraglottic larynx, sparing of the Anterior Segment, HSG and UES could further decrease the risk of radiation-induced aspiration, but this remains to be confirmed in clinical studies.

Radiotherapy and OncologyVol. 207
University Medical Center Groningen (NL), University of Groningen (NL), Amsterdam University Medical Centers (NL)
KWF Kankerbestrijding
Openalex Percentile: Top 2%
Dysphagia Assessment and Management
12.47
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