Human corneal organoid has a limbal function that supplies epithelium to the cornea with limbal deficiency
Our data suggest that corneal organoids de-differentiated to gain a limbal phenotype and functionally supplied corneal epithelium in a rabbit limbal deficiency model for up to 1 month.
Authors
- Takefumi Yamaguchi (ORCID: https://orcid.org/0000-0002-2546-2813)
- Kazunari Higa (ORCID: https://orcid.org/0000-0002-2015-3480)
- Shigeto Shimmura (ORCID: https://orcid.org/0000-0002-0992-4862)
- Masatoshi Hirayama (ORCID: https://orcid.org/0000-0003-3653-6344)
- Reona Kimoto
- Mifuyu Ishiwata
Institutions
- Fujita Health University (JP)
- Tokyo Dental College Ichikawa General Hospital (JP)
- Keio University Hospital (JP)
Publication Details
- Journal
- Regenerative Therapy
- Published
- 2025-03-29
- DOI
- https://doi.org/10.1016/j.reth.2025.03.004
- Citations
- 1
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.36