A comparative study of different parameter estimation methods for predictive models of Normal Tissue Complication Probability (NTCP) of radiation-induced temporal lobe injury following intensity-modulated radiotherapy in nasopharyngeal carcinoma
Bayesian Estimation (BE) is the best parameter estimation method among the three parameter estimation methods. The Poisson-NTCP model based on BE exhibited the best fit to the data in predicting post-IMRT incidence of TLI in NPC.
Authors
- Lei Zeng (ORCID: https://orcid.org/0000-0001-6517-8772)
- Xianming He (ORCID: https://orcid.org/0000-0003-2940-3703)
- Jiayin Wu (ORCID: https://orcid.org/0000-0002-7937-478X)
- Z. Y. Xu (ORCID: https://orcid.org/0000-0001-8626-1276)
- Yuze Liu (ORCID: https://orcid.org/0009-0002-6903-0294)
- Rong-Huan Hu (ORCID: https://orcid.org/0000-0001-9445-6743)
- Lei Tao (ORCID: https://orcid.org/0000-0002-8863-0044)
- Su Deng
- Zilin Huang (ORCID: https://orcid.org/0000-0002-1643-1994)
- Jian-Wu Ding (ORCID: https://orcid.org/0000-0001-7882-1309)
- Jian-Ze Zhang
- Jiali Hu (ORCID: https://orcid.org/0009-0007-2469-5520)
- Qi-Wei Luo
- H. Ouyang
- Mengmeng Liu (ORCID: https://orcid.org/0000-0002-0726-6675)
Institutions
- Nanchang University (CN)
- Sichuan University (CN)
- Jiangxi Agricultural University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-03-29
- DOI
- https://doi.org/10.1186/s12885-025-13906-6
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Beijing Xisike Clinical Oncology Research Foundation
- Natural Science Foundation of Jiangxi Province