Uterine carcinosarcomas case series of rare uterine malignancy

Primary malignant mixed Müllerian tumor (MMMT) of the ovary is a rare and highly aggressive neoplasm predominantly affecting postmenopausal women. MMMT is a biphasic tumor comprising both epithelial and mesenchymal components and is associated with significantly higher mortality compared to epithelial ovarian neoplasms. Patients typically present with symptoms such as vaginal bleeding, abdominal pain, and a palpable mass. Surgery remains the primary treatment modality, while adjuvant therapies, including chemotherapy and radiotherapy, play a crucial role in improving locoregional control and managing distant metastasis. Due to the rarity of these tumors, there is limited literature on their optimal therapeutic management. This series aims to analyse the clinical presentations and treatment outcomes of patients diagnosed with this uncommon uterine cancer treated at our hospital.

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Publication Details

Journal
International Journal of Research in Medical Sciences
Published
2025-03-29
DOI
https://doi.org/10.18203/2320-6012.ijrms20250995
Primary Topic
Uterine Myomas and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Uterine carcinosarcomas case series of rare uterine malignancy

Balaji Shewalkar, Punita Pant, Jitendra Patel, Dhiraj Meshram
International Journal of Research in Medical Sciences
Uterine Myomas and Treatments
article

Uterine carcinosarcomas case series of rare uterine malignancy

Balaji Shewalkar, Punita Pant, Jitendra Patel, Dhiraj Meshram
article en

Abstract

Primary malignant mixed Müllerian tumor (MMMT) of the ovary is a rare and highly aggressive neoplasm predominantly affecting postmenopausal women. MMMT is a biphasic tumor comprising both epithelial and mesenchymal components and is associated with significantly higher mortality compared to epithelial ovarian neoplasms. Patients typically present with symptoms such as vaginal bleeding, abdominal pain, and a palpable mass. Surgery remains the primary treatment modality, while adjuvant therapies, including chemotherapy and radiotherapy, play a crucial role in improving locoregional control and managing distant metastasis. Due to the rarity of these tumors, there is limited literature on their optimal therapeutic management. This series aims to analyse the clinical presentations and treatment outcomes of patients diagnosed with this uncommon uterine cancer treated at our hospital.

International Journal of Research in Medical SciencesVol. 13(4)
Rajarshee Chhatrapati Shahu Maharaj Government Medical College and CPR Hospital Kolhapur (IN)
Openalex Percentile: Top 91%
Uterine Myomas and Treatments
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