Chemical profiling and mechanistic insights into the antibacterial efficacy of Melaleuca cajuputi leaf extract
The findings of this study indicated that the methanolic extract of M. cajuputi leaves displayed potent antibacterial activity against Klebsiella pneumoniae, S. agalactiae, and S. aureus. The molecular docking analysis reveals significant binding interactions between the identified compounds and the target bacterial proteins, highlighting the potential of M. cajuputi as a novel source of anti-infectives targeting bacterial infections.
Authors
- Wan Rosli Wan Ishak (ORCID: https://orcid.org/0000-0001-7650-0499)
- Shajarahtunnur Jamil (ORCID: https://orcid.org/0000-0001-6188-9817)
- Hasmah Abdullah (ORCID: https://orcid.org/0000-0003-2550-0354)
- Musa Isah (ORCID: https://orcid.org/0000-0002-4468-9335)
- Mohd Dasuki Sul’ain (ORCID: https://orcid.org/0000-0002-0063-7648)
- Wan‐Nor‐Amilah Wan Abdul Wahab (ORCID: https://orcid.org/0000-0002-1339-362X)
- Ahmad Naqib Shuid (ORCID: https://orcid.org/0000-0002-8907-4350)
- Nordina Syamira
- Mahamad Shabudin
Institutions
- Universiti Sains Malaysia (MY)
- Abdullahi Fodio University of Science and Technology (NG)
- University of Technology Malaysia (MY)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2025-03-29
- DOI
- https://doi.org/10.1186/s12906-025-04790-5
- Citations
- 2
- Primary Topic
- Hibiscus Plant Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.11