Infiltrating B-cell subtypes and associated hub genes in nasopharyngeal carcinoma identified from integrated single-cell, bulk RNA-sequencing, and immunohistochemical data
A high infiltrating density of B cells showed strong prognostic value in patients with NPC. Naïve B cells may play an important role in tumor immunity for NPC.
Authors
- Tianzhu Lu (ORCID: https://orcid.org/0000-0002-1524-7909)
- Fangyan Zhong (ORCID: https://orcid.org/0000-0002-0766-5721)
- Lin Zhang (ORCID: https://orcid.org/0000-0003-3825-4973)
- Junjun Chen (ORCID: https://orcid.org/0000-0002-1549-7991)
- Xiaopeng Xiong (ORCID: https://orcid.org/0000-0003-2214-5326)
- Xiaochang Gong
- Chunhong Guan
- Zhiliang Liu (ORCID: https://orcid.org/0000-0001-5914-5667)
- Jingao Li (ORCID: https://orcid.org/0000-0002-0389-7576)
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Jiangxi Provincial Cancer Hospital (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-03-29
- DOI
- https://doi.org/10.1186/s41065-025-00414-7
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Jiangxi Province