Infection toxicity assessment of tumor necrosis factor α inhibitors in the treatment of IBD: a real-world study based on the US food and drug administration adverse events reporting system (FAERS)

Compared with other control therapies, TNF-α inhibitors have the strongest infectious toxicity signal. Compared with other TNF-α inhibitors, golimumab has the strongest infectious toxicity signal. When using TNF-α inhibitors to treat IBD, infection-related AEs should be vigilant.

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Publication Details

Journal
Expert Opinion on Drug Safety
Published
2025-03-29
DOI
https://doi.org/10.1080/14740338.2025.2486309
Citations
2
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
3.63
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article

Infection toxicity assessment of tumor necrosis factor α inhibitors in the treatment of IBD: a real-world study based on the US food and drug administration adverse events reporting system (FAERS)

Mengling Ouyang, Yazheng Zhao, Shupeng Zou, Qian Cheng et al.
2 citations
Expert Opinion on Drug Safety
Inflammatory Bowel Disease
3.63
article

Infection toxicity assessment of tumor necrosis factor α inhibitors in the treatment of IBD: a real-world study based on the US food and drug administration adverse events reporting system (FAERS)

Mengling Ouyang, Yazheng Zhao, Shupeng Zou, Qian Cheng, Zeyu Yao, Minghui Sun, Xuan Shi
article en
2 citations

Abstract

Compared with other control therapies, TNF-α inhibitors have the strongest infectious toxicity signal. Compared with other TNF-α inhibitors, golimumab has the strongest infectious toxicity signal. When using TNF-α inhibitors to treat IBD, infection-related AEs should be vigilant.

Expert Opinion on Drug Safety
Tongji Hospital (CN), Huazhong University of Science and Technology (CN)
Zero hunger
Openalex Percentile: Top 9%
Inflammatory Bowel Disease
3.63
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