A CONTROLLED CASE STUDY OF INFLAMMATORY MARKERS WITH NADI TARANGINI AS A SCREENING TEST IN PRANAVAHA SROTAS DUSHTI WITH SPECIAL REFERENCE TO COPD

Lung insults due to infections, allergens, dust, and tobacco smoking are the causative factors in lung injury and damage to the inner structures.These permanent changes in Bronchi, Bronchioles, and alveoli result in COPD [1].Ayurved look at this as Pranavaha Srotodushti janit vyadhi, especially in Shwasa and Kasa vyadhi types.High values of Cytokines (Inflammatory proteins) found in COPD result in a complex process of vascular stiffness due to changes in collagen abnormalities with loss of elastin proteins in vessels.Arterial stiffness is advanced due to an ageing factor resulting in arterial layer damage and arteriosclerosis [2].Arteries lose elasticity with bad collagen in structures that indicate stiffness.It got triggered due to periodical stress factors either.It was observed that arterial stiffness in different pathological situations and diseases can result in conflicting cardiovascular consequences than other pathophysiological factors [2].High pulse pressure, Raised Load in the Left Ventricle, and the pressure gradient that moves the coronary perfusion are the most important reasons for Arterial stiffness consequences [3].