BILOSOME: NOVEL VESICULAR CARRIER

Oral administration remains the most popular means of drug administration as far as patient compliance is concerned.After oral administration, most of the biological therapeutics (proteins/peptides) and vaccines have poor performance due to poor solubility or degradation in the gastrointestinal tract (GIT).Tremendous research in the last decade has made the bilosomes now acts as potential carrier system to tremendous research.Bilosomes are niosome like colloidal carrier system containing bile salts.Bilosomeshave developed as a potential carrier system for transdermal and parenteral targeted drug delivery and oral vaccine delivery.The present article covers various aspects related to the novel vesicular system that is based on bile salts called bilosomes, for targeted drug delivery systems.It includes information related to introduction of bilosome, composition, material required, method of preparation, characterization methods, stability consideration, and applications.