Dual-pathway tumor radiosensitization strategy based on engineered bacteria capable of targeted delivery of AuNPs and specific hypoxia alleviation
An effective strategy based on an integrated nanosystem (PCM@AuNPs) for radiosensitization through multiple pathways is developed. This novel engineered bacterial strategy holds great promise for enhancing radiosensitization in cancer therapy.
Authors
- Lingling Lei
- Meng Du (ORCID: https://orcid.org/0000-0002-1333-0581)
- Mingjie Li (ORCID: https://orcid.org/0000-0001-7245-9644)
- Zhiyi Chen (ORCID: https://orcid.org/0009-0009-9569-7560)
- Haonan Xu
Institutions
- Changsha Central Hospital (CN)
- University of South China (CN)
Publication Details
- Journal
- Journal of Nanobiotechnology
- Published
- 2025-03-29
- DOI
- https://doi.org/10.1186/s12951-025-03329-7
- Citations
- 10
- Primary Topic
- Cancer Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 12.33
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China