A Randomized, Controlled Clinical Pilot Study to Evaluate the Efficacy of Pushkaramoola (Inula racemosa Hook. f.) as a Monotherapy in Reducing Fever in Pediatric Patients

Background: Fever is a common and distressing symptom in children, requiring prompt and effective management. To address this, a randomized, controlled clinical pilot study was conducted to investigate the efficacy and safety of Pushkaramoola Vati, a traditional Ayurvedic medicine mentioned in Arogya kalpa druma, in reducing fever in pediatric patients. The study enrolled 20 pediatric patients with mild to moderate fever, who were randomly assigned to receive either Pushkaramoola Vati or Paracetamol. Objectives: The primary objectives of the study were to evaluate the efficacy of Pushkaramoola Vati in reducing fever and associated symptoms, assess its safety in pediatric patients, and compare its effects with those of Paracetamol. The study's expected outcomes are to provide preliminary data on the efficacy and safety of Pushkaramoola Vati as a potential treatment option for fever in pediatric patients. Result: The results will help determine whether Pushkaramoola Vati is a viable alternative to conventional antipyretics like Paracetamol. Overall assessment of the trial drug shows a Moderate improvement ie improvement was found in 50%-75% of signs and symptoms. Conclusion: This research has the potential to contribute significantly to the management of fever in children, offering a natural and safe treatment option for parents and healthcare providers. Keywords: Pushkaramoola vati, Fever