Role of <scp>ACTN3</scp> Gene <i>rs1815739</i> Polymorphism and Its Effects on Mandibular Morphogenesis

ACTN3 577XX polymorphism is more common among individuals with skeletal Class II malocclusion and short ramal height in the Dravidian population. It results in decreased protein expression in the masseteric muscle, which contributes to variations in sagittal and vertical facial dimensions.

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Journal
Orthodontics and Craniofacial Research
Published
2025-03-29
DOI
https://doi.org/10.1111/ocr.12919
Primary Topic
Genetics and Physical Performance
Type
article
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article

Role of ACTN3 Gene rs1815739 Polymorphism and Its Effects on Mandibular Morphogenesis

A. Sumathi Felicita, Shantha Sundari, Vijayashree Priyadharsini Jayaseelan, Aravind Kumar Subramanian et al.
Orthodontics and Craniofacial Research
Genetics and Physical Performance
article

Role of ACTN3 Gene rs1815739 Polymorphism and Its Effects on Mandibular Morphogenesis

A. Sumathi Felicita, Shantha Sundari, Vijayashree Priyadharsini Jayaseelan, Aravind Kumar Subramanian, Ashwin Mathew George
article en

Abstract

ACTN3 577XX polymorphism is more common among individuals with skeletal Class II malocclusion and short ramal height in the Dravidian population. It results in decreased protein expression in the masseteric muscle, which contributes to variations in sagittal and vertical facial dimensions.

Orthodontics and Craniofacial ResearchVol. 28(4)
Saveetha University (IN)
Openalex Percentile: Top 93%
Genetics and Physical Performance
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