Integrative network pharmacology, transcriptomics, and proteomics reveal the material basis and mechanism of the Shen Qing Weichang Formula against gastric cancer
This study uncovers a synergistic multi-component, multi-target, and multi-pathway regulatory mechanism of SQWCF in treating GC comprehensively, emphasizing its potential for therapeutic use and providing new insights into GC treatment.
Authors
- Aiguang Zhao
- Mingming Ren
- Yongfu Pan
- Xiaohong Zhu
- Yuanyuan Chen (ORCID: https://orcid.org/0000-0002-7953-1845)
- Yi Wang
- Yan Xu (ORCID: https://orcid.org/0009-0006-4348-5169)
- Ruohan Zhao (ORCID: https://orcid.org/0009-0005-2105-8193)
- Nida Cao
- Fangqi Ma
- Xiaoyu Sun (ORCID: https://orcid.org/0009-0000-9365-3171)
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Longhua Hospital Shanghai University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2025-03-29
- DOI
- https://doi.org/10.1186/s13020-025-01091-4
- Citations
- 5
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 7.79
Funders
- Program for Innovation Team Building at Institutions of Higher Education in Chongqing
- National Outstanding Youth Science Fund Project of National Natural Science Foundation of China
- Collaborative Innovation Center for Modern Science and Technology and Industrial Development of Jiangxi Traditional Medicine