Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

The fourth Industrial Revolution facilitates a symbiotic relationship between computational techniques and material development, with special emphasis in the domain of bioinspired materials. This initiative aims to propel interdisciplinary research by integrating computational technology with biomaterials, expediting advancements in fabrication and design. Computational design and simulations also offer an expansive landscape to engineer the next‐generation biomaterials utilizing nuclei‐acid based materials, spanning from the molecular to macroscopic levels, guided by specific molecular dynamics principles. This review aims to provide a succinct overview of prevailing computational techniques and multiscale simulations utilized in design of ribonucleic acid (RNA)‐based nanomaterials. By elucidating the interplay between structure and function, computational approaches facilitate the creation of biomimetic design and structures with tailored properties and functionalities for diverse applications. It underscores interdisciplinary collaborations, wherein insights from natural biomaterials inspire the rational design and synthesis of novel hierarchical structures using computational methodologies. Through a systematic exploration of current research paradigms, this review endeavors to delineate pathways for future innovation and advancement in the field of RNA‐based materials, fostering transformative impacts across sectors such as healthcare, biotechnology, and beyond.