The fragility index of randomized controlled trials in advanced/metastatic renal cell cancer

Not all RCTs associated with a/mRCC are as statistically robust as previously considered and should therefore be construed carefully. We suggest that additional reporting of FI in urological RCTs as a supplement to the P-value to assist readers in concluding reliably by considering the fragility of the outcomes.

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Publication Details

Journal
Urologic Oncology Seminars and Original Investigations
Published
2025-03-29
DOI
https://doi.org/10.1016/j.urolonc.2025.03.003
Primary Topic
Renal cell carcinoma treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

The fragility index of randomized controlled trials in advanced/metastatic renal cell cancer

Haotian Wei, Jiacheng Jin, Jianbo Wang, Yingwei Bi et al.
Urologic Oncology Seminars and Original Investigations
Renal cell carcinoma treatment
article

The fragility index of randomized controlled trials in advanced/metastatic renal cell cancer

Haotian Wei, Jiacheng Jin, Jianbo Wang, Yingwei Bi, Liang Zhu, Rui Wang, Yuxin Liu, Z. Zhai, Kewen Qu, Qing Ma
article en

Abstract

Not all RCTs associated with a/mRCC are as statistically robust as previously considered and should therefore be construed carefully. We suggest that additional reporting of FI in urological RCTs as a supplement to the P-value to assist readers in concluding reliably by considering the fragility of the outcomes.

Urologic Oncology Seminars and Original InvestigationsVol. 43(5)
Dalian Medical University (CN), Second Hospital of Tianjin Medical University (CN), First Affiliated Hospital of Dalian Medical University (CN), Tianjin Medical University (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 91%
Renal cell carcinoma treatment
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