Quantitative susceptibility mapping of the human carotid artery: Assessing sensitivity to elastin and collagen ex vivo
Tissue magnetic susceptibility in diseased human carotid arteries was shown to be significantly correlated with the dominant microstructural components of pathological human cadaver samples-elastin and collagen. Knowing that elastin and collagen are disrupted in vascular disease progression, QSM offers clinically translatable potential for novel disease biomarkers.
Authors
- Karin Shmueli (ORCID: https://orcid.org/0000-0001-7520-2975)
- Alan J. Stone (ORCID: https://orcid.org/0000-0002-5188-4323)
- Caitríona Lally (ORCID: https://orcid.org/0000-0003-4141-1685)
- Brooke Tornifoglio (ORCID: https://orcid.org/0000-0002-4359-9012)
Institutions
- University College Dublin (IE)
- Royal College of Surgeons in Ireland (IE)
- Trinity College Dublin (IE)
- Beaumont Hospital (IE)
- Advanced Materials and BioEngineering Research (IE)
- University College London (GB)
Publication Details
- Journal
- Magnetic Resonance in Medicine
- Published
- 2025-03-28
- DOI
- https://doi.org/10.1002/mrm.30500
- Citations
- 2
- Primary Topic
- Cerebrovascular and Carotid Artery Diseases
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- European Commission
- H2020 European Research Council