The antiprotease Spink7 promotes inflammation resolution by modulating multiple proteases activities during wound healing
Maintaining an endogenous balance between Spink7 and its target proteases is a crucial checkpoint for regulating inflammation resolution during healing. Therefore, manipulating levels of Spink7 might be an effective treatment for impaired wounds caused by inflammatory dysregulation.
Authors
- Xiaofan Lv (ORCID: https://orcid.org/0000-0002-0085-9507)
- Guojian Wang (ORCID: https://orcid.org/0000-0001-5934-4594)
- Tao Wang (ORCID: https://orcid.org/0000-0003-0975-8072)
- Na Zhao (ORCID: https://orcid.org/0009-0004-0712-1398)
- Shuang Long
- Junping Wang (ORCID: https://orcid.org/0000-0001-5905-0940)
- Yongping Su
- Xinze Ran
Institutions
- Army Medical University (CN)
- Chongqing University (CN)
Publication Details
- Journal
- Clinical and Translational Medicine
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1002/ctm2.70291
- Citations
- 4
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.10
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Natural Science Foundation of Chongqing