Evaluation of a targeted next-generation sequencing–based <i>CYP2D6</i> genotyping method compared with Sanger sequencing and multiplex ligation-dependent probe amplification
The NGS-based CYP2D6 genotyping method showed good performance, suggesting its potential utility in clinical practice. Including CYP2D6 in an NGS panel for patients who may use drugs metabolized by CYP2D6 may provide additional useful information.
Authors
- Sollip Kim (ORCID: https://orcid.org/0000-0003-0474-5897)
- Sail Chun (ORCID: https://orcid.org/0000-0002-5792-973X)
- Hyun‐Ki Kim (ORCID: https://orcid.org/0000-0002-3299-5298)
- Won-Kyu Choi
- Woochang Lee
Institutions
- University of Ulsan (KR)
- Ulsan University Hospital (KR)
Publication Details
- Journal
- Laboratory Medicine
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1093/labmed/lmae115
- Primary Topic
- Pharmacogenetics and Drug Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00