Cardiometabolic complications after Cushing’s disease remission

Surgical remission leads to faster and sustained improvements in clinical phenotype. However, obesity, arterial hypertension, and dyslipidemia do not completely revert in five years, especially during medical treatment. Most comorbidities persist despite UFC normalization, due to impaired LNSC: the recovery of cortisol rhythms confirms the remission of hypercortisolism.

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Publication Details

Journal
Journal of Endocrinological Investigation
Published
2025-03-26
DOI
https://doi.org/10.1007/s40618-025-02572-x
Citations
5
Primary Topic
Pituitary Gland Disorders and Treatments
Type
article
Field-Weighted Citation Impact
6.47

Funders

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article

Cardiometabolic complications after Cushing’s disease remission

Mattia Barbot, Alessandro Mondin, Laura Lizzul, Filippo Ceccato et al.
5 citations
Journal of Endocrinological Investigation
Pituitary Gland Disorders and Treatments
6.47
article

Cardiometabolic complications after Cushing’s disease remission

Mattia Barbot, Alessandro Mondin, Laura Lizzul, Filippo Ceccato, Pierluigi Mazzeo, Irene Tizianel, Giacomo Voltan, Carla Maria Scaroni
article en
5 citations

Abstract

Surgical remission leads to faster and sustained improvements in clinical phenotype. However, obesity, arterial hypertension, and dyslipidemia do not completely revert in five years, especially during medical treatment. Most comorbidities persist despite UFC normalization, due to impaired LNSC: the recovery of cortisol rhythms confirms the remission of hypercortisolism.

Journal of Endocrinological InvestigationVol. 48(7)
University of Padua (IT)
Università degli Studi di Padova
Good health and well-being
Openalex Percentile: Top 4%
Pituitary Gland Disorders and Treatments
6.47
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