[Study on the mechanism of apoptosis mediated by acid sensitive ion channel 1 through extracellular signal regulation of kinase 5 signaling pathway and mitochondrial disorder pathway].

After the activation of ASIC1 channel protein, calcium ions could enter the cells and act as a second messenger molecule to regulate apoptosis of nucleus pulposus cells by ERK5 signaling pathway and mitochondrial disorder pathway.

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Publication Details

Journal
PubMed
Published
2025-03-25
DOI
https://doi.org/10.12200/j.issn.1003-0034.20230722
Citations
1
Primary Topic
Traditional Chinese Medicine Analysis
Type
article
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article

[Study on the mechanism of apoptosis mediated by acid sensitive ion channel 1 through extracellular signal regulation of kinase 5 signaling pathway and mitochondrial disorder pathway].

Zhao-Hui Jin, Xiangyan Luo, Chi Zhang
1 citations
PubMed
Traditional Chinese Medicine Analysis
article

[Study on the mechanism of apoptosis mediated by acid sensitive ion channel 1 through extracellular signal regulation of kinase 5 signaling pathway and mitochondrial disorder pathway].

Zhao-Hui Jin, Xiangyan Luo, Chi Zhang
article en
1 citations

Abstract

After the activation of ASIC1 channel protein, calcium ions could enter the cells and act as a second messenger molecule to regulate apoptosis of nucleus pulposus cells by ERK5 signaling pathway and mitochondrial disorder pathway.

PubMedVol. 38(3)
Jinhua Central Hospital (CN)
Traditional Chinese Medicine Analysis
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