Effects of Huoxue Chubi decoction on protein kinase B-mammalian target of rapamycin autophagy pathway in scleroderma Balb/c model mice.
HXCB can regulate autophagy by invigorating <i>Qi</i>and promoting blood circulation, thereby reducing blood stasis, facilitating new tissue generation, and contributing to scleroderma treatment. This effect may be attributed to the promotion of autophagy and enhancement of collagen degradation through the reduction of tissue oxidative stress elicited by HXCB.
Authors
- Xi Chen (ORCID: https://orcid.org/0000-0002-5807-4219)
- Hui Jia (ORCID: https://orcid.org/0000-0003-3955-6439)
- Zhang Runtian
- Jianhong Li (ORCID: https://orcid.org/0000-0002-7736-0333)
- Ruijie Wang (ORCID: https://orcid.org/0000-0001-9611-4974)
- Kaihui Zhang (ORCID: https://orcid.org/0000-0003-4799-9133)
- Duan Xingwu
- Q U Tiange
Institutions
- Zhejiang Chinese Medical University (CN)
- Shunyi Hospital of Beijing Traditional Chinese Medicine Hospital (CN)
- Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine (CN)
- First Affiliated Hospital Zhejiang University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-01
- DOI
- https://doi.org/10.19852/j.cnki.jtcm.2025.02.005
- Primary Topic
- Kruppel-like factors research
- Type
- article
- Field-Weighted Citation Impact
- 0.00