Body Composition Assessment Provides Prognostic Information in Patients With Cancer Affected by Chronic Graft vs. Host Disease
These data support that radiographic body composition measures provide prognostic information among patients with cancer affected by cGVHD post-HCT and suggest that high body fat % is a promising candidate for future study. These findings suggest that low skeletal muscle mass alone does not predict for poor outcomes in HCT patients with cGVHD as previously described in other cancers. Independent validation of this work is needed, including further studies based on CT chest to enhance application to a larger HCT population.
Authors
- Rawan Faramand (ORCID: https://orcid.org/0000-0001-7750-781X)
- Kevin Bigam (ORCID: https://orcid.org/0000-0002-8718-250X)
- Vickie E. Baracos (ORCID: https://orcid.org/0000-0002-9609-1001)
- Farhad Khimani (ORCID: https://orcid.org/0000-0003-4828-4711)
- Martine Extermann (ORCID: https://orcid.org/0000-0003-4381-1199)
- Asmita Mishra (ORCID: https://orcid.org/0000-0003-3065-4294)
- Xuefeng Wang (ORCID: https://orcid.org/0000-0001-5775-408X)
- Ram Thapa (ORCID: https://orcid.org/0000-0001-6128-4105)
- Joseph A. Pidala (ORCID: https://orcid.org/0009-0005-7693-7398)
Institutions
- University of Alberta (CA)
- Moffitt Cancer Center (US)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2025-03-28
- DOI
- https://doi.org/10.1002/jcsm.13759
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00