Efficacy of Primaquine for the Radical Cure of <i>Plasmodium vivax</i> Malaria in Northeast Myanmar and the Impact of Cytochrome P450 2D6 Genotypes

More than 75% of patients with vivax malaria in this region carried CYP2D6 alleles with an AS ≤1.25, suggesting the consideration for higher PQ doses.

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Publication Details

Journal
Clinical Infectious Diseases
Published
2025-03-27
DOI
https://doi.org/10.1093/cid/ciae482
Citations
4
Primary Topic
Malaria Research and Control
Type
article
Field-Weighted Citation Impact
7.51
Controls
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article

Efficacy of Primaquine for the Radical Cure of Plasmodium vivax Malaria in Northeast Myanmar and the Impact of Cytochrome P450 2D6 Genotypes

Liwang Cui, Chengqi Wang, Lynette Menezes, Weilin Zeng et al.
4 citations
Clinical Infectious Diseases
Malaria Research and Control
7.51
article

Efficacy of Primaquine for the Radical Cure of Plasmodium vivax Malaria in Northeast Myanmar and the Impact of Cytochrome P450 2D6 Genotypes

Liwang Cui, Chengqi Wang, Lynette Menezes, Weilin Zeng, Huaie Liu, Pallavi Malla, Yan Zhao, Zhaoqing Yang, Yaming Cao
article en
4 citations

Abstract

More than 75% of patients with vivax malaria in this region carried CYP2D6 alleles with an AS ≤1.25, suggesting the consideration for higher PQ doses.

Clinical Infectious DiseasesVol. 81(2)
Shenyang Medical College (CN), Kunming Medical University (CN), University of South Florida (US), First Affiliated Hospital of Kunming Medical University (CN), Center for Global Health (US), China Medical University (CN)
Good health and well-being
Openalex Percentile: Top 3%
Malaria Research and Control
7.51
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Efficacy of Primaquine for the Radical Cure of <i>Plasmodium vivax</i> Malaria in Northeast Myanmar and the Impact of Cytochrome P450 2D6 Genotypes — Liwang Cui, Chengqi Wang, et al. · Clinical Infectious Diseases (2025) | TGRS Research Map | TGRS