MALAT1 SNP (rs619586) shows a protective effect against type 1 diabetes mellitus, while the miR-146a SNP (rs57095329) is linked to an increased risk of developing the disease

For the first time, our investigation had shown the connection between MALAT1 (rs619586) and miRNA-146a (rs57095329) polymorphisms and the risk of development of T1DM in Egyptians.

Authors

Omayma O. Abdelaleem
Sara M. A. Massoud
Olfat Gamil Shaker (ORCID: https://orcid.org/0000-0002-3031-3599)
Ola N. Sayed
Sherin Khamis Hussein
Soha M. Hamdy
Heba A. Ibrahim

Institutions

Cairo University (EG)
Fayoum University (EG)

Publication Details

Journal: Molecular Biology Reports
Published: 2025-03-26
DOI: https://doi.org/10.1007/s11033-025-10404-7
Citations: 3
Primary Topic: Cancer-related molecular mechanisms research
Type: article
Field-Weighted Citation Impact: 2.81

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article

MALAT1 SNP (rs619586) shows a protective effect against type 1 diabetes mellitus, while the miR-146a SNP (rs57095329) is linked to an increased risk of developing the disease

Omayma O. Abdelaleem, Sara M. A. Massoud, Olfat Gamil Shaker, Ola N. Sayed et al.

Mar 26, 2025

3 citations

Molecular Biology Reports

Cancer-related molecular mechanisms research

2.81

article

MALAT1 SNP (rs619586) shows a protective effect against type 1 diabetes mellitus, while the miR-146a SNP (rs57095329) is linked to an increased risk of developing the disease

Omayma O. Abdelaleem, Sara M. A. Massoud, Olfat Gamil Shaker, Ola N. Sayed, Sherin Khamis Hussein, Soha M. Hamdy, Heba A. Ibrahim

March 26, 2025article en

3 citations

Abstract

For the first time, our investigation had shown the connection between MALAT1 (rs619586) and miRNA-146a (rs57095329) polymorphisms and the risk of development of T1DM in Egyptians.

Molecular Biology ReportsVol. 52(1)

Cairo University (EG), Fayoum University (EG)

Good health and well-being

Openalex Percentile: Top 10%

Cancer-related molecular mechanisms research

2.81

DOI Open Access PDF OpenAlex

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