Successful rapid desensitization to zoledronic acid in a multiple myeloma patient

Here, we demonstrate successful management with RD in an MM patient with HR to ZA, providing a valuable therapeutic option for patients experiencing such reactions. The effectiveness of RD to ZA was confirmed by the negative response to skin tests after 3 RD procedures. Nevertheless, further research is needed to refine RD protocols and establish their safety and efficacy for patients with HR to ZA. Standardized in vitro testing may also improve the diagnosis and management of ZA hypersensitivity.