Transcranial direct current stimulation treatment reduces, while repetitive transcranial magnetic stimulation treatment increases electroencephalography spike rates with refractory occipital lobe epilepsy: A case study

The study details the case of a patient suffering from epilepsy, located in the occipital region of the brain, who did not respond to several antiseizure medications. We treated with both transcranial direct current stimulation and repetitive transcranial magnetic stimulation. The transcranial direct current stimulation treatment resulted in a significant decrease in EEG spikes, yet the patient's condition worsened again after 2 weeks. We therefore used repetitive transcranial magnetic stimulation treatment, which, in fact, resulted in an increase in spike frequency. The results demonstrate both the potential benefits and risks of non-invasive brain stimulation as treatment in drug-resistant epilepsy.