Synthesis Of New Bromo Oxazepine Compounds, Biological Evaluation, Molecular Docking Studies, And Simulation Methodology For Anti-Skin Cancer.

Heterocyclic compounds are of particular interest, especially in the area of medical chemistry. The bulk of contemporary drugs do, in fact, include a heterocyclic ring. The seven-atom unsaturated heterocycles known as azepines have one spot where a nitrogen atom takes the place of a carbon atom. In a single pot, it is subjected to cyclization and has a fresh 2-aminophenol substituted for the aromatic ring. A possible skin cancer treatment drug (2VCI), 4,5-diaryl isoxazole Hsp90 Chaperone inhibitors, are tested insilico docking studies against bromooxazepine derivatives.

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Publication Details

Journal
African Journal of Biomedical Research
Published
2024-12-24
DOI
https://doi.org/10.53555/ajbr.v27i6s.7214
Primary Topic
Synthesis and biological activity
Type
article
Field-Weighted Citation Impact
0.00
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article

Synthesis Of New Bromo Oxazepine Compounds, Biological Evaluation, Molecular Docking Studies, And Simulation Methodology For Anti-Skin Cancer.

B. Brindha
African Journal of Biomedical Research
Synthesis and biological activity
article

Synthesis Of New Bromo Oxazepine Compounds, Biological Evaluation, Molecular Docking Studies, And Simulation Methodology For Anti-Skin Cancer.

B. Brindha
article en

Abstract

Heterocyclic compounds are of particular interest, especially in the area of medical chemistry. The bulk of contemporary drugs do, in fact, include a heterocyclic ring. The seven-atom unsaturated heterocycles known as azepines have one spot where a nitrogen atom takes the place of a carbon atom. In a single pot, it is subjected to cyclization and has a fresh 2-aminophenol substituted for the aromatic ring. A possible skin cancer treatment drug (2VCI), 4,5-diaryl isoxazole Hsp90 Chaperone inhibitors, are tested insilico docking studies against bromooxazepine derivatives.

African Journal of Biomedical Research
Good health and well-being
Openalex Percentile: Top 81%
Synthesis and biological activity
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Synthesis Of New Bromo Oxazepine Compounds, Biological Evaluation, Molecular Docking Studies, And Simulation Methodology For Anti-Skin Cancer. — B. Brindha · African Journal of Biomedical Research (2024) | TGRS Research Map | TGRS