Oral Mucosal Calcified Nodule: Report of a Case and Review of the Literature

The oral mucosal calcified nodule (OMCN) is a rare soft tissue lesion with only 7 cases reported in the English literature. It typically presents in the pediatric population as an asymptomatic submucosal nodule of less than 2 cm size affecting the maxillary ridge or palate, though other sites are reported. The histopathology displays stratified squamous epithelium overlying fibrous connective tissue with embedded calcified aggregates bordered by variable numbers of multinucleated giant cells. Surgical excision is curative. In this report, we present a new case of OMCN, outline the characteristic histopathologic features and review the cases reported in the English literature.

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Journal
Pediatric and Developmental Pathology
Published
2025-03-28
DOI
https://doi.org/10.1177/10935266251325064
Primary Topic
Oral and Maxillofacial Pathology
Type
article
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article

Oral Mucosal Calcified Nodule: Report of a Case and Review of the Literature

Arthi Kumar, Denise Trochesset, Yasmin Ludianski
Pediatric and Developmental Pathology
Oral and Maxillofacial Pathology
article

Oral Mucosal Calcified Nodule: Report of a Case and Review of the Literature

Arthi Kumar, Denise Trochesset, Yasmin Ludianski
article en

Abstract

The oral mucosal calcified nodule (OMCN) is a rare soft tissue lesion with only 7 cases reported in the English literature. It typically presents in the pediatric population as an asymptomatic submucosal nodule of less than 2 cm size affecting the maxillary ridge or palate, though other sites are reported. The histopathology displays stratified squamous epithelium overlying fibrous connective tissue with embedded calcified aggregates bordered by variable numbers of multinucleated giant cells. Surgical excision is curative. In this report, we present a new case of OMCN, outline the characteristic histopathologic features and review the cases reported in the English literature.

Pediatric and Developmental PathologyVol. 28(4)
New York University (US)
Quality Education
Openalex Percentile: Top 92%
Oral and Maxillofacial Pathology
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