Levetiracetam Induced Acute Reversible Psychosis: A Case Report

Levetiracetam (Keppra) is a second-generation antiepileptic drug (AED) widely used for focal and generalized seizures due to its efficacy, favourable pharmacokinetics, and low risk of drug interactions.However, its neuropsychiatric side effects, including aggression, mood disturbances, and psychosis, are increasingly recognized.Keppra-induced psychosis (KIP) is a rare but serious adverse effect that can significantly impact patient safety and treatment adherence.While psychiatric symptoms associated with levetiracetam use have been described, reports of psychosis remain relatively uncommon.We present a case of Keppra-induced psychosis in a patient with no prior psychiatric history, emphasizing the importance of recognizing this rare but serious adverse effect.

Publication Details

Journal
Annals of Case Reports
Published
2024-09-22
DOI
https://doi.org/10.29011/2574-7754.102227
Citations
2
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Levetiracetam Induced Acute Reversible Psychosis: A Case Report

2 citations
Annals of Case Reports
Epilepsy research and treatment
article

Levetiracetam Induced Acute Reversible Psychosis: A Case Report

article en
2 citations

Abstract

Levetiracetam (Keppra) is a second-generation antiepileptic drug (AED) widely used for focal and generalized seizures due to its efficacy, favourable pharmacokinetics, and low risk of drug interactions.However, its neuropsychiatric side effects, including aggression, mood disturbances, and psychosis, are increasingly recognized.Keppra-induced psychosis (KIP) is a rare but serious adverse effect that can significantly impact patient safety and treatment adherence.While psychiatric symptoms associated with levetiracetam use have been described, reports of psychosis remain relatively uncommon.We present a case of Keppra-induced psychosis in a patient with no prior psychiatric history, emphasizing the importance of recognizing this rare but serious adverse effect.

Annals of Case ReportsVol. 9(5)
Openalex Percentile: Top 63%
Epilepsy research and treatment
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