ApoE [−/−] CA1-overexpressing knock-in mice aggravated atherosclerosis by increasing M1 macrophages
These findings revealed aggravated AS in ApoE [-/-] CA1-overexpressing mice and suggest that CA1 aggravates AS by increasing M1-type macrophages, a proinflammatory macrophage subtype.
Authors
- Xiaotian Chang (ORCID: https://orcid.org/0000-0002-7639-7740)
- Kehua Fang
- Jinbao Zong (ORCID: https://orcid.org/0000-0003-2282-6906)
- Hongji Zhou (ORCID: https://orcid.org/0000-0001-7741-8155)
- Changyuan Wang (ORCID: https://orcid.org/0000-0002-5669-1483)
- Yu Song (ORCID: https://orcid.org/0009-0008-0889-1289)
Institutions
- Qingdao University (CN)
- Liaoning Shihua University (CN)
- Affiliated Hospital of Qingdao University (CN)
- Qingdao Municipal Hospital (CN)
Publication Details
- Journal
- Atherosclerosis Plus
- Published
- 2025-03-29
- DOI
- https://doi.org/10.1016/j.athplu.2025.03.003
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00