Construction of chiral γ-lactam scaffolds <i>via</i> asymmetric cascade [3 + 2] annulation of <i>N</i>-alkoxyacrylamides catalyzed by a chiral-at-metal rhodium complex

An efficient asymmetric cascade [3 + 2] annulation of N -alkoxyacrylamides with α,β-unsaturated 2-acyl imidazoles catalyzed by a chiral-at-metal rhodium complex has been developed.

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Publication Details

Journal
Organic Chemistry Frontiers
Published
2025-01-01
DOI
https://doi.org/10.1039/d5qo00276a
Citations
1
Primary Topic
Asymmetric Hydrogenation and Catalysis
Type
article
Field-Weighted Citation Impact
0.54
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article

Construction of chiral γ-lactam scaffolds via asymmetric cascade [3 + 2] annulation of N-alkoxyacrylamides catalyzed by a chiral-at-metal rhodium complex

Jun Gong, Rui-Qiu Zhang, Lu H, Wan-Shun Cheng et al.
1 citations
Organic Chemistry Frontiers
Asymmetric Hydrogenation and Catalysis
0.54
article

Construction of chiral γ-lactam scaffolds via asymmetric cascade [3 + 2] annulation of N-alkoxyacrylamides catalyzed by a chiral-at-metal rhodium complex

Jun Gong, Rui-Qiu Zhang, Lu H, Wan-Shun Cheng, Heng‐Lin Cui, Xiaobo Wang, Chen Yang, Ping Xue, Yuhe Ke, Shiwu Li
article en
1 citations

Abstract

An efficient asymmetric cascade [3 + 2] annulation of N -alkoxyacrylamides with α,β-unsaturated 2-acyl imidazoles catalyzed by a chiral-at-metal rhodium complex has been developed.

Organic Chemistry FrontiersVol. 12(14)
Shihezi University (CN), Hubei University of Science and Technology (CN), Xinjiang University (CN)
Openalex Percentile: Top 38%
Asymmetric Hydrogenation and Catalysis
0.54
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