A deep learning approach to remotely assessing essential tremor with handwritten images
Essential tremor (ET) is the most prevalent movement disorder, with its incidence increasing with age, significantly impacting motor functions and quality of life. Traditional methods for assessing ET severity are often time-consuming, subjective, and require in-person visits to medical facilities. This study introduces a novel deep learning-based approach for remotely assessing ET severity using handwriting images, which improves both efficiency and accessibility. We collected approximately 1000 high-quality Archimedean spiral handwriting images from patients in both medical institutions and home settings, creating a robust and diverse dataset. A transfer learning-based model, ETSD-Net, was developed and trained to evaluate ET severity. The model achieved an accuracy of 88.44%, demonstrating superior performance over baseline models. Our approach offers a cost-effective, scalable, and reliable solution for ET assessment, particularly in remote or resource-limited settings, and provides a valuable contribution to the development of more accessible diagnostic tools for movement disorders.
Authors
- Zhengbo Zhang (ORCID: https://orcid.org/0000-0001-9218-5644)
- Chenbin Ma (ORCID: https://orcid.org/0000-0003-1945-9332)
- Longsheng Pan (ORCID: https://orcid.org/0000-0002-1033-1802)
- Wenjing Yang (ORCID: https://orcid.org/0009-0001-1823-5292)
- Tian Yuan (ORCID: https://orcid.org/0000-0003-3111-365X)
- Di Wu (ORCID: https://orcid.org/0000-0002-6870-443X)
- Yumeng Peng (ORCID: https://orcid.org/0009-0009-9920-7354)
- Song Han (ORCID: https://orcid.org/0000-0001-7138-4214)
- Ping He (ORCID: https://orcid.org/0000-0002-2544-9803)
- Zijing Zeng
- Ying Shi (ORCID: https://orcid.org/0000-0001-8445-2300)
- Lixuan Li (ORCID: https://orcid.org/0009-0007-4702-4666)
Institutions
- Nankai University (CN)
- Chinese PLA General Hospital (CN)
- PLA Academy of Military Science (CN)
- 303 Hospital of People's Liberation Army (CN)
- Beihang University (CN)
Publication Details
- Journal
- Scientific Reports
- Published
- 2025-03-28
- DOI
- https://doi.org/10.1038/s41598-025-94729-0
- Citations
- 4
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.56
Funders
- National Natural Science Foundation of China