Optical coherence tomography findings of macula and neural changes in cryptococcal meningitis

Papilledema may or may not be present depending on the timing of the evaluation, and the ophthalmologic manifestations of CM with papilledema can be well observed. However, changes in the optic nerve head (ONH) and peripapillary structures in CM patients with no papilledema can be detected by optical coherence tomography. Parameters such as pRNFLT, pGCL++T, pGCL+T and pCT may provide useful evidence for the early detection of structures and neural impairments in patients with CM.