A CHALLENGING CASE OF VOLUMINOUS OVARIAN FIBROTHECOMA MIMICKING MALIGNANCY: DEMONS-MEIGS SYNDROME

Demons-Meigs syndrome is a rare clinical entity characterized by a benign ovarian tumor associated with ascites and pleural effusion, which resolve after tumor removal. We report the case of a 68-year-old postmenopausal woman diagnosed with a large ovarian fibrothecoma, initially suspected of malignancy due to massive ascites and an elevated CA-125 level. The final histopathological diagnosis confirmed a benign fibrothecoma. Surgical treatment led to a complete resolution of symptoms, supporting the diagnosis of Demons-Meigs syndrome. This case highlights the challenges in distinguishing fibrothecoma from malignant ovarian tumors and underscores the importance of histopathological confirmation.

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Publication Details

Journal
International Journal of Advanced Research
Published
2025-02-28
DOI
https://doi.org/10.21474/ijar01/20520
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
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article

A CHALLENGING CASE OF VOLUMINOUS OVARIAN FIBROTHECOMA MIMICKING MALIGNANCY: DEMONS-MEIGS SYNDROME

M. Bendahhou Idrissi, Abbas Banani, C. Bouchikhi, N. Mamouni et al.
International Journal of Advanced Research
Ovarian cancer diagnosis and treatment
article

A CHALLENGING CASE OF VOLUMINOUS OVARIAN FIBROTHECOMA MIMICKING MALIGNANCY: DEMONS-MEIGS SYNDROME

M. Bendahhou Idrissi, Abbas Banani, C. Bouchikhi, N. Mamouni, K. Laaouini, Sanâa Errarhay, W. Garrouani
article en

Abstract

Demons-Meigs syndrome is a rare clinical entity characterized by a benign ovarian tumor associated with ascites and pleural effusion, which resolve after tumor removal. We report the case of a 68-year-old postmenopausal woman diagnosed with a large ovarian fibrothecoma, initially suspected of malignancy due to massive ascites and an elevated CA-125 level. The final histopathological diagnosis confirmed a benign fibrothecoma. Surgical treatment led to a complete resolution of symptoms, supporting the diagnosis of Demons-Meigs syndrome. This case highlights the challenges in distinguishing fibrothecoma from malignant ovarian tumors and underscores the importance of histopathological confirmation.

International Journal of Advanced ResearchVol. 13(02)
Openalex Percentile: Top 91%
Ovarian cancer diagnosis and treatment
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