Analysis of drug transporter expression in syncytiotrophoblast derived from human placental stem cells: Expression and function of efflux transporters
This study showed higher transporter expression in ST-TS<sup>CT</sup> than that in a traditional trophoblast model. Furthermore, the functional expression of efflux transporters was observed. ST-TS<sup>CT</sup> is valuable for investigating placental transport functions.
Authors
- Akira Ueda (ORCID: https://orcid.org/0000-0002-1603-7970)
- Ayako Furugen (ORCID: https://orcid.org/0000-0002-2081-5827)
- Masaki Kobayashi (ORCID: https://orcid.org/0000-0003-3762-2391)
- Katsuya Narumi (ORCID: https://orcid.org/0000-0002-1633-7041)
- Takeshi Umazume (ORCID: https://orcid.org/0000-0001-9236-9945)
- Ayako Nishimura (ORCID: https://orcid.org/0000-0002-0309-4845)
- Riko Sawada
Institutions
- Hokkaido University (JP)
- Hokkaido Pharmaceutical University (JP)
- Hokkaido University Hospital (JP)
Publication Details
- Journal
- Placenta
- Published
- 2025-03-29
- DOI
- https://doi.org/10.1016/j.placenta.2025.03.021
- Citations
- 4
- Primary Topic
- Drug Transport and Resistance Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 4.18