The Gut Microbiome: A Key Player in Obesity and Type 2 Diabetes - Mechanisms and Therapeutic Potential

Obesity and diabetes have emerged as global health crises, with their prevalence reaching epidemic proportions.With increasing food intake and sedentary lifestyles contributing significantly to the obesity epidemic, recent research has highlighted the critical role of gut microbiota in the development and progression of these metabolic disorders.The gut microbiome is increasingly recognized as a key player in obesity and diabetes through its involvement in food absorption, energy regulation, low-grade inflammation, and insulin resistance.This review paper explores the latest advancements in understanding the gut microbiota's role in the development of obesity and type 2 diabetes (T2D), also focusing on the therapeutic potential of modulating gut microbiota to mitigate the impacts of these metabolic diseases, elucidating the underlying mechanisms and implications for human health.