Successful Treatment of Nail Lichen Planus with Roflumilast 0.3% Cream: A Case Report

Nail lichen planus is considered a true nail emergency resulting in destruction of the nails. Nail lichen planus is frequently resistant to treatments and has a high recurrence rate. This is a case report of a patient with lichen planus involving all of her fingernails, which exhibited 100% improvement following the daily application of the PDE4 inhibitor, topical roflumilast 0.3% cream, once daily.

Authors

Publication Details

Journal
Journal of Dermatology Research
Published
2025-03-29
DOI
https://doi.org/10.46889/jdr.2025.6111
Primary Topic
Oral Health Pathology and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Successful Treatment of Nail Lichen Planus with Roflumilast 0.3% Cream: A Case Report

Edward M Klepper
Journal of Dermatology Research
Oral Health Pathology and Treatment
article

Successful Treatment of Nail Lichen Planus with Roflumilast 0.3% Cream: A Case Report

Edward M Klepper
article en

Abstract

Nail lichen planus is considered a true nail emergency resulting in destruction of the nails. Nail lichen planus is frequently resistant to treatments and has a high recurrence rate. This is a case report of a patient with lichen planus involving all of her fingernails, which exhibited 100% improvement following the daily application of the PDE4 inhibitor, topical roflumilast 0.3% cream, once daily.

Journal of Dermatology Research
Openalex Percentile: Top 93%
Oral Health Pathology and Treatment
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