Genomic landscape of childhood acute lymphoblastic leukemia in Malaysia: insights from array-CGH

Our study indicates that array-CGH is able to identify and characterize the CNVs responsible for the pathogenesis of childhood ALL. However, further studies are required to determine the pathogenic implications of VUS in the development of childhood ALL.

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Publication Details

Journal
Molecular Cytogenetics
Published
2025-03-28
DOI
https://doi.org/10.1186/s13039-025-00709-4
Citations
1
Primary Topic
Acute Lymphoblastic Leukemia research
Type
article
Field-Weighted Citation Impact
1.88

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article

Genomic landscape of childhood acute lymphoblastic leukemia in Malaysia: insights from array-CGH

Zahidah Abu Seman, Asmida Isa, Elizabeth George, Azli Ismail et al.
1 citations
Molecular Cytogenetics
Acute Lymphoblastic Leukemia research
1.88
article

Genomic landscape of childhood acute lymphoblastic leukemia in Malaysia: insights from array-CGH

Zahidah Abu Seman, Asmida Isa, Elizabeth George, Azli Ismail, Fadly Ahid, Ezalia Esa, Yuslina Mat Yusoff, Nor Rizan Kamaluddin, Zubaidah Zakaria, Maha Mohammed, Wong Nyuk Moi
article en
1 citations

Abstract

Our study indicates that array-CGH is able to identify and characterize the CNVs responsible for the pathogenesis of childhood ALL. However, further studies are required to determine the pathogenic implications of VUS in the development of childhood ALL.

Molecular CytogeneticsVol. 18(1)
Ministry of Health (MY), Universiti Putra Malaysia (MY), Universiti Sains Malaysia (MY), Institute for Medical Research (MY), Universiti Teknologi MARA (MY)
Ministry of Higher Education, Malaysia, Kementerian Kesihatan Malaysia
Openalex Percentile: Top 17%
Acute Lymphoblastic Leukemia research
1.88
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