ITGA3–MET interaction promotes papillary thyroid cancer progression via ERK and PI3K/AKT pathways
ITGA3 promotes PTC cell proliferation and migration by cooperating with MET to activate MET-ERK and MET-PI3K-AKT signalling. ITGA3-MET cooperation may serve as a potential therapeutic target.
Authors
- Lingzhu Xie (ORCID: https://orcid.org/0000-0002-3591-5767)
- Bin Liang (ORCID: https://orcid.org/0000-0001-9131-5478)
- Youmian Lan
- Rui Liang
- Xiaolong Wei (ORCID: https://orcid.org/0000-0001-6119-1400)
- X. Weng (ORCID: https://orcid.org/0000-0001-5629-4894)
- Haipeng Guo (ORCID: https://orcid.org/0000-0001-5431-517X)
- Hanwei Peng (ORCID: https://orcid.org/0000-0002-6754-2627)
- Chaoqun Hong
- Dongyang Huang (ORCID: https://orcid.org/0000-0002-9971-8906)
- Dongchen Liu (ORCID: https://orcid.org/0000-0001-5176-9272)
- Xuhong Song
- Xiaoqi Liao
- Muyuan Liu (ORCID: https://orcid.org/0000-0001-5064-1373)
Institutions
- Shantou University (CN)
- Cancer Hospital of Shantou University Medical College (CN)
- Shantou University Medical College (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1080/07853890.2025.2483379
- Citations
- 9
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 11.65
Funders
- National Natural Science Foundation of China
- Guangdong Medical Research Foundation
- Shantou Science and Technology Project