Genetic test results and one-year developmental outcomes of fetuses with congenital heart disease
SNP array analysis enhances the detection of genetic etiologies in CHD, assisting in the precise localization of chromosomal anomalies and candidate gene screening. It is effective for prenatal diagnosis in CHD fetuses. Fetuses with isolated cardiac structural abnormalities show lower rates of chromosomal anomalies and CNVs and generally have favorable one-year developmental outcomes, underlining the importance of SNP array analysis in managing CHD outcomes.
Authors
- Xiaofang Lan
- Penglong Chen
- Bo Zhou (ORCID: https://orcid.org/0000-0002-7973-1185)
- Qunda Shan
- Shuangshuang Shen (ORCID: https://orcid.org/0009-0004-9063-0184)
- Jiao Liu (ORCID: https://orcid.org/0009-0005-3286-8861)
- Hui Hu (ORCID: https://orcid.org/0000-0002-4954-6843)
- Xiangdong Zhang (ORCID: https://orcid.org/0000-0001-5893-2888)
Institutions
- Lishui Maternity and Child Health Care Hospital (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2025-03-28
- DOI
- https://doi.org/10.3389/fped.2025.1518784
- Citations
- 2
- Primary Topic
- Congenital Heart Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.71