Synthesis of 3, 3-Di(indolyl)indolin-2-one in the Presence of Iron Nanocatalysts

3, 3-di(indolyl)indolin-2-one derivatives have attracted the attention of researchers due to their various biological and medicinal applications. Due to the significant importance of indole compounds, various methods with different conditions and catalysts have been used for their synthesis. However, some of these reactions have disadvantages, such as low efficiency, long reaction time, use of toxic solvents, etc. In the study, iron nanocatalysts have been used as a suitable catalyst to prepare 3, 3-di(indolyl)indolin-2-one derivatives. This method has many advantages compared to other methods and it completes the reaction in a shorter time and with a higher yield, as described in this article.

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Publication Details

Journal
Letters in Organic Chemistry
Published
2025-03-28
DOI
https://doi.org/10.2174/0115701786368671250215200344
Primary Topic
Synthesis of Indole Derivatives
Type
article
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article

Synthesis of 3, 3-Di(indolyl)indolin-2-one in the Presence of Iron Nanocatalysts

Bita Baghernejad, Seyyedeh Masoumeh Zakariaie
Letters in Organic Chemistry
Synthesis of Indole Derivatives
article

Synthesis of 3, 3-Di(indolyl)indolin-2-one in the Presence of Iron Nanocatalysts

Bita Baghernejad, Seyyedeh Masoumeh Zakariaie
article en

Abstract

3, 3-di(indolyl)indolin-2-one derivatives have attracted the attention of researchers due to their various biological and medicinal applications. Due to the significant importance of indole compounds, various methods with different conditions and catalysts have been used for their synthesis. However, some of these reactions have disadvantages, such as low efficiency, long reaction time, use of toxic solvents, etc. In the study, iron nanocatalysts have been used as a suitable catalyst to prepare 3, 3-di(indolyl)indolin-2-one derivatives. This method has many advantages compared to other methods and it completes the reaction in a shorter time and with a higher yield, as described in this article.

Letters in Organic ChemistryVol. 22(11)
Payame Noor University (IR)
Openalex Percentile: Top 95%
Synthesis of Indole Derivatives
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