Increased amounts of cell-free DNA released from a culture with a high content of cancer stem cells
These findings highlight the importance of cfDNA in carcinogenesis and its potential as a biomarker and therapeutic target, especially given the role of CSCs in drug resistance and tumor aggressiveness.
Authors
- Lucía Taja‐Chayeb (ORCID: https://orcid.org/0000-0002-9592-8527)
- Catalina Trejo‐Becerril (ORCID: https://orcid.org/0000-0002-5107-1568)
- Rocío Morales‐Bárcenas (ORCID: https://orcid.org/0000-0002-0963-4021)
- Ileana J. Fernández-Domínguez
- Enrique Pérez‐Cárdenas (ORCID: https://orcid.org/0000-0002-4896-4111)
- Talía Wegman-Ostrosky (ORCID: https://orcid.org/0000-0002-3207-6697)
- Alejandro Zentella‐Dehesa (ORCID: https://orcid.org/0000-0002-5595-1466)
- Claudia Haydeé Saraí Caro-Sánchez (ORCID: https://orcid.org/0000-0003-3792-6758)
- Alfonso Dueñas‐González (ORCID: https://orcid.org/0000-0002-2956-645X)
- Horacio López-Basabe
Institutions
- Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (MX)
- Instituto Nacional de Cancerología (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-03-28
- DOI
- https://doi.org/10.3389/fcell.2025.1499936
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00