Revisiting a Rare Anomaly Described 25 Years Ago in the <i>AJNR</i>: A Journey from Pediatric Hemifacial Microsomia and Middle Cranial Fossa Aplasia to CSF-Lymphatic Fistula and Spontaneous Intracranial Hypotension as an Adult
This report presents a unique case of a 39-year-old woman with a congenital unilateral aplasia of the middle cranial fossa floor associated with atypical hemifacial microsomia, initially described in a case report at age 14, who later developed a transosseous CSF-lymphatic fistula through the C1 vertebral body. Dynamic CT cisternography confirmed the diagnosis, and a transnasal percutaneous fibrin glue occlusion successfully reversed the patient's brain sag and improved her symptoms. This case highlights the evolving understanding of CSF dynamics and the diagnostic and therapeutic challenges posed by rare CSF leak variants.
Authors
- Debayan Bhaumik (ORCID: https://orcid.org/0000-0002-9324-9256)
- Peter Lennarson (ORCID: https://orcid.org/0009-0001-5953-6446)
- Andrew L. Callen (ORCID: https://orcid.org/0000-0003-2315-7767)
- Michael L. Cunningham (ORCID: https://orcid.org/0000-0003-2277-654X)
- David Zander
- Ashoke Khanwalkar (ORCID: https://orcid.org/0000-0001-9960-7758)
- Danielle Wilhour
- Premal Trivedi (ORCID: https://orcid.org/0000-0002-3219-0393)
- Samantha L. Pisani Petrucci
Institutions
- Seattle Children's Hospital (US)
- University Radiology (US)
- University of Colorado Anschutz Medical Campus (US)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2025-03-27
- DOI
- https://doi.org/10.3174/ajnr.a8760
- Citations
- 1
- Primary Topic
- Neurosurgical Procedures and Complications
- Type
- article
- Field-Weighted Citation Impact
- 0.00