Circulating miRNAs are associated with successful bone regeneration
Our study indicates that regardless of the treatment group, success or lack of bone regeneration is associated with a distinct expression pattern of circulating microRNAs. Further research is needed to determine whether their levels in the blood can be used as predictive factors of successful bone regeneration.
Authors
- Patrick Heimel (ORCID: https://orcid.org/0000-0002-2499-325X)
- Claudia Lindner (ORCID: https://orcid.org/0000-0001-9396-3436)
- Matthias Hackl (ORCID: https://orcid.org/0000-0002-4136-7293)
- Gabriele Leinfellner
- Stefan Tangl (ORCID: https://orcid.org/0000-0002-9023-4745)
- Dominik Hanetseder (ORCID: https://orcid.org/0000-0003-2625-3842)
- Heinz R. Redl (ORCID: https://orcid.org/0000-0003-1654-462X)
- Marianne Pultar
- Darja Marolt (ORCID: https://orcid.org/0000-0003-3638-4619)
- Barbara Schädl (ORCID: https://orcid.org/0000-0002-6712-6279)
- Amelie Frischer
- Carina Kampleitner (ORCID: https://orcid.org/0000-0003-3072-5072)
- Regina Grillari‐Voglauer (ORCID: https://orcid.org/0000-0002-5487-2838)
- Fergal J. O’Brien (ORCID: https://orcid.org/0000-0003-2030-8005)
- Johannes Grillari (ORCID: https://orcid.org/0000-0001-5474-6332)
- J. Howard Frank (ORCID: https://orcid.org/0000-0003-2903-8726)
- Simon Sperger (ORCID: https://orcid.org/0000-0001-6985-7334)
- Johanna Gamauf
Institutions
- Institute of Molecular Biotechnology (AT)
- Royal College of Surgeons in Ireland (IE)
- Trinity College Dublin (IE)
- Ludwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA (AT)
- Advanced Materials and BioEngineering Research (IE)
- Evercyte (Austria) (AT)
- National Institute of Chemistry (SI)
- Austrian Cluster for Tissue Regeneration (AT)
- Ludwig Boltzmann Institute for Digital Health and Prevention (AT)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2025-03-28
- DOI
- https://doi.org/10.3389/fbioe.2025.1527493
- Citations
- 2
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 1.87