Comparison of the efficacy and impact on coagulation function of different rituximab dosage regimens in the treatment of membranous nephropathy

Both 1 g and 375 mg/m<sup>2</sup> RTX regimens exhibit comparable efficacy and safety in IMN patients, without significantly affecting coagulation function. Treatment should be individualized based on factors such as BMI, diabetes history, urine protein levels, and PLA2R levels to optimize coagulation risk management.

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Publication Details

Journal
American Journal of Translational Research
Published
2025-01-01
DOI
https://doi.org/10.62347/wqab1378
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
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article

Comparison of the efficacy and impact on coagulation function of different rituximab dosage regimens in the treatment of membranous nephropathy

Xin Zhang
American Journal of Translational Research
Renal Diseases and Glomerulopathies
article

Comparison of the efficacy and impact on coagulation function of different rituximab dosage regimens in the treatment of membranous nephropathy

Xin Zhang
article en

Abstract

Both 1 g and 375 mg/m<sup>2</sup> RTX regimens exhibit comparable efficacy and safety in IMN patients, without significantly affecting coagulation function. Treatment should be individualized based on factors such as BMI, diabetes history, urine protein levels, and PLA2R levels to optimize coagulation risk management.

American Journal of Translational ResearchVol. 17(3)
Baoji City Central Hospital (CN)
Zero hunger
Openalex Percentile: Top 92%
Renal Diseases and Glomerulopathies
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Comparison of the efficacy and impact on coagulation function of different rituximab dosage regimens in the treatment of membranous nephropathy — Xin Zhang · American Journal of Translational Research (2025) | TGRS Research Map | TGRS