Post-COVID-19 Effects on Chronic Gastritis and Gastric Cellular and Molecular Characteristics in Male Mice
SARS-CoV-2 infection indirectly leads to profound and post-acute COVID-19 alterations in the stomach at the cellular and molecular levels, resulting in adverse outcomes following co-infection with SARS-CoV-2 and Hpylori. Our results show that 2 prevalent pathogens of humans elicit a negative synergistic effect and provide evidence of the risk of severe chronic gastritis in the post-COVID-19 era.
Authors
- Chanyang Uhm
- James R. Goldenring (ORCID: https://orcid.org/0000-0002-7833-2940)
- Jeon‐Soo Shin (ORCID: https://orcid.org/0000-0002-8294-3234)
- Jooyeon Oh (ORCID: https://orcid.org/0000-0003-1701-7792)
- Jun-Young Seo (ORCID: https://orcid.org/0000-0003-4004-2013)
- Heeju Oh
- Jeong Jin Kim (ORCID: https://orcid.org/0000-0002-8886-5441)
- Jun-Won Yun (ORCID: https://orcid.org/0000-0002-0155-4190)
- In Ho Park (ORCID: https://orcid.org/0000-0003-2190-5469)
- Je Kyung Seong (ORCID: https://orcid.org/0000-0003-1177-6958)
- Kyungrae Cho
- Haengdueng Jeong (ORCID: https://orcid.org/0000-0002-9218-7372)
- Sang‐Ho Jeong (ORCID: https://orcid.org/0000-0001-9061-6236)
- Ki Taek Nam (ORCID: https://orcid.org/0000-0001-5292-1280)
- Donghun Jeon
- Ji-Ho Park (ORCID: https://orcid.org/0000-0001-5233-430X)
- Jun Won Park (ORCID: https://orcid.org/0000-0003-4677-1786)
- Sunghee Kim (ORCID: https://orcid.org/0000-0002-2644-8466)
- Jiseon Kim (ORCID: https://orcid.org/0000-0002-0979-0278)
Institutions
- Seoul National University (KR)
- Gyeongsang National University (KR)
- Yonsei University (KR)
- Vanderbilt University (US)
- New Generation University College (ET)
- Gyeongsang National University Hospital (KR)
- National University College (PR)
- Yonsei University Health System (KR)
Publication Details
- Journal
- Cellular and Molecular Gastroenterology and Hepatology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.jcmgh.2025.101511
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- National Research Foundation of Korea
- National Institute of Food and Drug Safety Evaluation