Features of innate and adaptive immunity in patients with COVID-19 coronavirus infection
Objective : to study the immunological parameters of patients who had suffered from COVID-19 in moderate form 1 and 6 months after recovery. Materials and method s: 60 patients hospitalized with the diagnosis of "COVID-19, moderate form; complication: interstitial pneumonia" were examined. Immunological parameters were assessed 1 month and 6 months after recovery. Comparison group: 20 healthy volunteers. Results: after six months, signs of immune dysfunction continue to persist in the immune status, consisting in a violation of the processes of differentiation and proliferation of immunocompetent cells. Conclusion : the need for immunological monitoring in people who have had COVID-19 for 6 months in order to identify immunodeficiency conditions and prevent infectious diseases against this background is shown.
Authors
- Dmitrii V. Siziakin (ORCID: https://orcid.org/0000-0001-7125-1374)
- N.A. Skripkina (ORCID: https://orcid.org/0000-0003-0165-6805)
- V. Ya. Zakurskayа (ORCID: https://orcid.org/0000-0003-0837-1538)
- L. P. Sizyakinа (ORCID: https://orcid.org/0000-0001-5716-4397)
Institutions
- Rostov State Medical University (RU)
- City Hospital № 1 named after. ON. Semashko (RU)
Publication Details
- Journal
- Medical Herald of the South of Russia
- Published
- 2025-01-22
- DOI
- https://doi.org/10.21886/2219-8075-2025-16-1-106-111
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 0.00