Systemic EBV+ T-Cell Lymphoma of Childhood with Hemophagocytic Lymphohistiocytosis in a Patient with a Highly Complex Karyotype
SEBVTCL can be challenging to diagnose due to the similarity in clinical and pathological presentations. In virtually all cases reported in the literature, an abnormal karyotype has been reported to be the most important prognostic factor. We propose that in cases with diagnostic ambiguity, an abnormal karyotype can help favor SEBVTCL over EBV+ HLH.
Authors
- Joanna Chaffin
- Emilia Guzman
- Reema Kashif (ORCID: https://orcid.org/0009-0001-4570-9799)
- Patrick Maher
- Rachel D. Burnside (ORCID: https://orcid.org/0000-0002-0063-2281)
Institutions
- University of Florida (US)
Publication Details
- Journal
- Genes
- Published
- 2025-03-27
- DOI
- https://doi.org/10.3390/genes16040382
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00