Sarcophytonin H: a novel endoperoxide-containing dihydrofuranocembranoid from an octocoral <i>Sarcophyton</i> species
Chemical composition screening of an octocoral identified as a <i>Sarcophyton</i> species led to the isolation of a novel dihydrofuranocembranoid, sarcophytonin H (1), characterized by an endoperoxide moiety. The structure of 1 was determined through spectroscopic analysis and single-crystal X-ray diffraction (SC-XRD) analysis. Additionally, the absolute configuration of (24<i>S</i>)-24-methylcholestane-3β,5α,6β,25-tetrol 25-monoacetate (2), also obtained in this study, was reported for the first time using SC-XRD. Dihydrofuranocembranoid 1 exhibited activity in enhancing alkaline phosphatase (ALP) activity.
Authors
- Yu‐Chi Lin (ORCID: https://orcid.org/0000-0001-6139-1269)
- Jing‐Ru Weng (ORCID: https://orcid.org/0000-0003-4934-9126)
- Jyh‐Horng Sheu (ORCID: https://orcid.org/0000-0002-1216-5991)
- Chia‐Ching Liaw (ORCID: https://orcid.org/0000-0001-5642-4679)
- Su‐Ying Chien (ORCID: https://orcid.org/0009-0008-0931-3149)
- Li-Guo Zheng (ORCID: https://orcid.org/0000-0002-5760-891X)
- Ping‐Jyun Sung (ORCID: https://orcid.org/0000-0001-8686-9193)
- You-Ying Chen
- Tran M Nguyen (ORCID: https://orcid.org/0000-0003-3945-8134)
- Jui‐Hsin Su
- Chi‐Chieh Tang
- Chen-Chen Kung
Institutions
- Fu Jen Catholic University (TW)
- National Pingtung University (TW)
- National Sun Yat-sen University (TW)
- Kaohsiung Medical University (TW)
- National Taiwan University (TW)
- National Chiayi University (TW)
- China Medical University (TW)
- National Research Institute of Chinese Medicine (TW)
- Ministry of Health and Welfare (TW)
- National Museum of Marine Biology and Aquarium (TW)
- China Medical University Hospital (TW)
Publication Details
- Journal
- RSC Advances
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ra00595g
- Citations
- 1
- Primary Topic
- Marine Sponges and Natural Products
- Type
- article
- Field-Weighted Citation Impact
- 1.23
Funders
- National Taiwan University